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Before using this medication.women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage.trouble getting order ponstel 250). Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy.this medication should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.
Because serious GI bleeding.hepatotoxicity.and renal injury can occur without warning symptoms or signs.consider monitoring patients on long-term NSAID treatment with a CBC and a chemistry profile checked periodically (see WARNINGS. Gastrointestinal Bleeding.Ulceration and Perforation.and Hepatotoxicity ).
Advise females of reproductive potential who desire pregnancy that NSAIDs.including Ponstel.may be associated with a reversible delay in ovulation. (see PRECAUTIONS. Carcinogenesis.Mutagenesis.Impairment of Fertility).
The elimination half-life of mefenamic acid is approximately two hours. Half-lives of metabolites I and Order ponstel 250 have not been precisely reported.but appear to be longer than the parent compound. The metabolites may order ponstel 250 in patients with renal or hepatic failure. The mefenamic acid glucuronide may bind irreversibly to plasma proteins. Because both renal and hepatic excretions are significant pathways of elimination.dosage adjustments in patients with renal or hepatic dysfunction may be necessary. Ponstel should not be administered to patients with pre-existing renal disease or in patients with significantly impaired renal function ( see WARNINGS. Renal Toxicity and Hyperkalemia) .
USES. Mefenamic acid is used for the short-term treatment of mild to moderate pain from various conditions. It is also used to decrease pain and blood loss from menstrual periods.Mefenamic acid is known as a nonsteroidal anti-inflammatory drug (NSAID).OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used to treat gout attacks.
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